S-adenosyl-methionine (SAM-e) is a naturally-occurring compound in the body which promotes methylation, the process whereby methyl groups (one atom of carbon and 3 of hydrogen) are transferred from one molecule to another. Methylation is essential for many enzymatic processes and SAM-e is the most active of all methyl donors. Indeed, SAM-e has been the subject of dozens of clinical studies involving thousands of patients.
SAM-e plays a crucial role in conjunctive tissue synthesis; it eases joint pain, promotes mobility and protects cartilage from damage. In 2002, an American government agency, the Agency for Healthcare Research and Quality (AHRQ) concluded that SAM-e was 80% more effective than a placebo at relieving osteo-arthritis pain, and as effective as non-steroidal anti-inflammatories (NSAIDs) at treating osteo-arthritis. NSAIDs are associated with serious side-effects while SAM-e has health benefits for the whole body:
We introduced SAM-e into Europe in 1998 and while its price has now been reduced by over 70%, it remains an expensive nutrient. It should be recognized that:
Like SAM-e, other substances with excellent therapeutic potential are also available to buy as nutritional supplements. Super Quercetin, for example, is a quercetin concentrate with antioxidant, anti-inflammatory, anti-carcinogenic and cardio-protective properties. Two natural extracts also recognised for their therapeutic efficacy are French oak, for reducing fatigue and improving mood, and hypericum, for combatting mild to moderate depression.
Alternative spelling/keywords : SAM e, SAMe, SAM_e, SAM
october 26 2024
produit extrêmement efficace ,je recommande très surement
extremely effective product, I definitely recommend it
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september 11 2024
Après 1 mois de traitement aucun effet positif.
After 1 month of treatment, no positive effect.
Hello Jean-Marc,
Thank you for sharing your opinion on our SAM-e 400 mg - 60 gastro tablets.
It is true that results can vary between individuals, and we understand that this can be frustrating. If you would like to discuss your concerns or explore other options that might better meet your needs, please do not hesitate to contact our customer service. We are here to help you.
We appreciate your feedback, which helps us improve our products and services.
Sincerely,
Gaëlle - Supersmart
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march 26 2024
très bon produit. j'utilise plusieurs mois en intervalle. mais chère
Very good product. I use it for several months at intervals. But expensive.
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march 22 2024
un vrai trésor pour la santé avec une action quasi immédiate
a true treasure for health with an almost immediate effect
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march 20 2024
c'est ,une vraie potion magique!
It's a real magic potion!
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Bonjour Jean-Marc,
Merci d'avoir partagé votre avis sur notre SAM-e 400 mg - 60 comprimés gastro.
Il est vrai que les résultats peuvent varier selon les individus, et nous comprenons que cela puisse être frustrant. Si vous souhaitez discuter de vos préoccupations ou explorer d'autres options qui pourraient mieux répondre à vos besoins, n'hésitez pas à contacter notre service client. Nous sommes là pour vous aider.
Nous apprécions votre retour, qui nous aide à améliorer nos produits et services.
Cordialement,
Gaëlle - Supersmart