Organic Trametes versicolor (polypore mushroom) supplement

Organic Turkey Tail is a high-quality dietary supplement composed of extract of Turkey Tail. This medicinal mushroom offers high immunostimulant and antioxidant potency.

Though it remains little-known in the West, it is a popular remedy in traditional Chinese and Japanese medicine. It is also used in modern Asian medicine, particularly alongside anti-cancer treatments.

It is the mushroom’s content of the complex carbohydrates polysaccharides and numerous phenolic compounds which are responsible for its considerable efficacy.

Pro-immunity mushroom that resembles a turkey tail

What is Trametes versicolor?

Turkey Tail, or to give its scientific name, Trametes versicolor, is a lignivore mushroom which means it feeds on wood. It usually grows on the trunks of deciduous trees like beeches and birches, in a wide variety of places and in many different climates.

Its common name Turkey Tail comes from its upright shape and graded shades of brown reminiscent of a wild turkey’s tail fan. It is also known as Coriolus versicolor, kawaratake (‘beside-the-river mushroom’ in Japanese) and yun-zhi (‘cloud mushroom’ in Chinese).

A mushroom rich in PSP and PSK polysaccharides

Turkey tail’s powerful immunostimulant, anti-infectious and anti-tumour effects are due to its many nutrients (1-2). In particular, it has a wide range of polysaccharides. These natural carbohydrates, formed from many smaller simple sugars or monosaccharides, are known for their numerous health benefits.

More specifically, Turkey Tail contains:

• Polysaccharide-peptides (PSP). These long-chain sugars are able to stimulate macrophage and T lymphocyte activity (3) and are also thought to have anti-cancer properties. (4)
• And polysaccharide-K or Krestin (PSK). These complex carbohydrates have been used for more than 30 years as a chemotherapy agent in several Asian countries (5).

What benefits does the supplement Organic Turkey Tail offer?

It helps improve the immune response

First and foremost, Organic Turkey Tail helps boost the body’s immune response.

The polysaccharides in the mushroom Trametes versicolor are known to be effective at activating immune cells. (6) These compounds, referred to as ‘biological response modifiers’, also act by improving the expression of cytokines and chemokines (7-8).

Stimulating immune function naturally increases the body’s protection by making it more resistant to pathogens.

Turkey Tail: effective against infection

Turkey Tail also acts directly against various aggressors such as viruses and bacteria. One study noted its potential as an anti-influenza and anti-herpes agent, and even attributed it with a ‘high therapeutic index’. (9)

This mushroom is also useful in fighting multiple bacteria (10). Let’s not forget that antibiotics, the drugs prescribed for eliminating or limiting bacteria, are themselves often extracts of medicinal fungi.

The polysaccharide-peptides in Trametes versicolor are, amongst others, able to eliminate harmful gut bacteria and thus play a genuine prebiotic role in the body. (11-12) This ability to regulate intestinal microbiota further contributes to this mushroom’s immunomodulatory power. (13)

A mushroom with recognised anti-tumour properties

In Asia, turkey tail is regularly used as a preventive substance and adjunct treatment for several types of cancer. (14-16) A Chinese study of more than 4000 subjects observed positive effects on overall survival and quality of life of cancer patients. (17)

Taking Turkey Tail may significantly increase patient survival, particularly in those with breast, stomach or colon cancer undergoing chemotherapy. (18-19). This mushroom also has recognised therapeutic potential for cervical, uterine and pancreatic cancer as well as leukaemia and malignant lymphoma. (20-21)

Meanwhile, an American study examining the anti-cancer properties of Trametes versicolor found its polysaccharide components to offer benefits as an adjuvant cancer therapy, as part of an overall treatment and secondary prevention strategy. (22)

Turkey tail’s anti-tumour properties are due to several factors:

• Its PSPs improve the ability of T lymphocytes, key immune response cells, to penetrate tumours (23).
• The complex carbohydrates in Coriolus versicolor accelerate the rate of apoptosis, ie, the elimination of cancer cells (without damaging healthy cells) (24-25).
• As we know, cancer stem cells represent the tiny proportion of cells that survive anti-cancer treatment. If they spread, they can boost tumour growth polysaccharide-peptides have an ability to combat cancer stem cells, thus inhibiting the formation and spread of tumours. This chemo-preventive property of orally-administered PSPs was revealed in a study on prostate cancer (26).
• These polysaccharides also counteract the fall in white cell numbers caused by a medication used in the treatment of various cancers () (27).
• Anti-cancer therapy reduces the body’s immune defences in general; taking Turkey Tail will help restore healthy immunity. (28)

A powerful antioxidant, rich in phenolic compounds

Lastly, Organic Turkey Tail also helps to combat oxidative stress. As we know, this oxidation process unleashes a flood of free radicals in the body, which result in cellular ageing and can lead to chronic inflammation. Turkey tail, a potent antioxidant, counteracts this damage. (29)

This mushroom is in fact a rich natural source of antioxidants, containing numerous phenolic compounds: one study revealed that the phenol-acids in an aqueous extract of turkey tail helped to, amongst others, inhibit DPPH and OH free radicals, as well as acetylcholinesterase (AchE). (30) Among the other phenolic compounds found in Turkey Tail are flavonoids, the well-known and highly effective antioxidants (31-32), not forgetting its high content of terpenoids or terpenes, another family of antioxidant metabolites. (33-34)

Finally, the results of a 2015 study suggest that extract of Trametes versicolor may also have anti-genotoxic properties – in other words, its components may be able to directly protect a cell’s genome. (35)