Supplement for supporting nitric oxide (blood dilation)

Nitric oxide is a gas molecule released by the body to relax the smooth muscle surrounding blood vessels. When the latter contract, blood flow decreases, and when they relax and dilate, blood circulates more freely.

What is nitric oxide?

Nitric oxide is present in every movement we make throughout life. Its importance was recognised in 1992 when the journal Science named it ‘Molecule of the Year'. In 1998, three researchers were awarded the Nobel Prize for Medicine for research into nitric oxide.

As we get older, our bodies produce less nitric oxide. This can lead to a number of diseases since nitric oxide's characteristics are not limited to the dilation of blood vessels and maintaining stable blood pressure. Nitric oxide is also active in the lungs: relaxing the smooth muscle enables a greater flow of oxygen to the lungs and pulmonary alveoli. Without this, respiration becomes more difficult and problems of breathlessness occur.

Nitric oxide is also a natural sex stimulant : in fact, adequate production in the penis is essential for achieving an erection. Nitric oxide supplementation is a simple and effective way of supporting sexual function and increasing sexual response both in men and women. Stimulation of nitric oxide is actually the main mode of action of some famous erectile dysfunction treatments.

Nitric oxide is produced from the amino acid L-arginine, particularly in its alpha ketoglutarate (AKG) form which is uniquely able to improve the process of conversion into NO.

• The combination L-arginine-L-citrulline increases levels of NO, both in the short and long term (due to L-citrulline's prolonged action). Combining these two substances optimises cardiac function and also improves immune response. The immune system is better-supported during recovery and has stronger resistance to germs and viruses. Arginine alpha ketoglutarate directly influences the activity and production of lymphocytes allowing nitric oxide to stimulate Natural Killer Cells to fight certain forms of pathogenic bacteria.
• L-citrulline, in its ‘malate' form, helps eliminate metabolic waste products produced by the muscles when exercising ; the reduction in these combustion waste products ensures increased stamina during exercise. Citrulline's action complements that of NO and allows it to regenerate.
• D-aspartic acid (DAA) is naturally present in the pituitary gland, the hypothalamus and the testicles. It stimulates luteinising hormone which acts as a neurotransmitter and stimulates testosterone production in the testicles. It is essential for energy production and maintenance.
• Agmatine sulfate perfectly complements aspartic acid and prevents over-activation of NMDA receptors which ensure transmission of electric signals between the brain cells and spinal cord. Agmatine is a by-product of arginine and is produced via the process of decarboxylation. It acts as a pump, encouraging increased NO levels in the soft endothelial tissue which surrounds the blood vessels, and thus helps prevent vein constriction. In addition, agmatine stimulates the release of NO and inhibits the enzymes that destroy it. The results are clear: agmatine produces prolonged, continuous muscle pump action. More effective than arginine, agmatine stimulates the release of LH and GH hormones making it a useful, pre-training aid for athletes. Last but not least, agmatine protects the nervous system and engenders well-being.

Nitric oxide formula also contains Vinitrox™, a powerful polyphenol extract from apples and grapes that has antioxidant and vasorelaxant properties, and is beneficial in sports nutrition. It acts synergistically with arginine, by stimulating endothelial production of NO, improving the latter's efficacy as a relaxant and cell oxygenator. Polyphenols reduce the harmful effects of free radicals generated during exercise, lowering levels of nitrotyrosine and thus promoting improved recovery.

Nitric Oxide Formula, with its simple ingredients but diverse effects, covers a wide symptomatology and offers multiple health benefits.